Scientists Tried to Clone Clones Forever. It Didn’t End Well

Countless scientists and at least a dozen high-concept sci-fi comedies over the past 30 years have speculated on the ...

Bionano Genomics, Inc. (BNGO) Q4 2025 Earnings Call Transcript

Good day, and welcome to the Bionano Fourth Quarter and Full Year 2025 Earnings Conference Call. Today's conference is being recorded. At this time, I would like to turn the conference over to Webb ...
ascopubs.org

Assessing the Detection Power of Genome-Wide Copy Number Variation Profiles in Prostate Cancer Using Simulated Shallow Whole-Genome Sequencing Data

SNF-CLIMEDIN: A Randomized Trial of Digital Support and Intervention in Patients With Advanced Non–Small Cell Lung Cancer. A Hellenic Cooperative Oncology Group Study Shallow whole-genome sequencing ...
Medical Xpress

DNA Copy Number Variations

Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help explain why African-American patients survive for half as long as their counterparts of European ...
EurekAlert!

DNA copy-number changes help melanoma develop resistance to immunotherapy, UCLA study finds

A study led by UCLA Health Jonsson Comprehensive Cancer Center investigators reveals how melanoma, the deadliest form of skin cancer, evolves to resist immunotherapy and identifies a potential ...
ascopubs.org

Characterization of copy number variations (CNV) patterns and pseudotime trajectories in high-grade serous ovarian cancer (HGSOC).

Neoadjuvant pamiparib in patients with newly diagnosed advanced ovarian cancer: A single-arm, prospective phase II trial. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This ...
Too Old to Operate

Mitochondrial DNA Copy Number Variation Signals Asthma Susceptibility

The following is a summary of “Mitochondrial DNA copy number variation in asthma risk, severity, and exacerbations,” published in the April 2025 issue of Journal of Allergy and Clinical Immunology by ...
IEEE

A New Genomic Wave Adjustment Method for DNA Copy Number Variation Detection

Abstract: DNA copy number variations (CNV) carry information on the mis-regulation of DNA replication in cancer cells, making the study of CNVs an indispensable component of cancer genome analysis.
PNAS

Copy number variation contributes to parallel local adaptation in an invasive plant

Using a population-genomic approach, we identified copy number variants (CNVs)—stretches of DNA that can be either present, absent, or in multiple copies—displaying parallel signatures of local ...
IEEE

COPCNVBD: An Integrated Approach for Somatic Copy Number Variation and Breakpoint Detection Using Whole Genome Sequencing Data

Abstract: Read depth (RD) signals anomaly-based copy number variation (CNV) detection methods using whole genome sequencing data are affected by the measurement scale and parameters, and the ...
Too Old to Operate

Patterns and variations of copy number alterations in acute myeloid leukemia: insights from the LeukAtlas database.

Recent pan-cancer analysis revealed the global pattern and potential aetiologies of copy number variation signatures in human cancers, particularly those derived from non-hematopoietic tissues. In ...