Delpacibart etedesiran led mostly to mild to moderate adverse events in a phase I/II trial of myotonic dystrophy type 1, but two serious events occurred. The antibody-oligonucleotide conjugate reduced ...
We’ve all been there. Knee-deep in a six-day bro split, halfway through your fourth set of lunges, wondering why you’re dedicating an entire session to a single muscle group. The DOMS are relentless, ...
Vaccine maker Biological E.’s 14-valent pneumococcal conjugate vaccine Pneubevax 14 (BE-PCV-14) has received World Health Organization (WHO) pre-qualification status. The PQ enables broader reach ...
ABBV-154, an antibody-drug conjugate comprising adalimumab conjugated to a proprietary glucocorticoid receptor modulator, shows potential for extending flare-free periods in patients with ...
MRG004A, a novel antibody-drug conjugate, elicited antitumor activity and had manageable toxicities when used in heavily pretreated patients with multiple tumor types with high tissue factor.
Bristol Myers Squibb has filled the antibody-drug conjugate (ADC) shaped hole in its pipeline by following the increasingly well-trodden path to China, handing SystImmune $800 million upfront for a ...
An effective, affordable, multivalent meningococcal conjugate vaccine is needed to prevent epidemic meningitis in the African meningitis belt. Data on the safety and immunogenicity of NmCV-5, a ...
Sequential intravesical gemcitabine and docetaxel versus bacillus Calmette-Guérin for the treatment of high-risk, treatment-naïve, non-muscle invasive bladder cancer. This is an ASCO Meeting Abstract ...
A phase Ia/Ib study of CBP-1008, a bispecific ligand drug conjugate, in patients with advanced solid tumors. This is an ASCO Meeting Abstract from the 2022 ASCO Annual Meeting I. This abstract does ...
Eli Lilly is looking to create new drugs for immunology and other diseases by combining antibodies and oligonucleotides—or short DNA or RNA molecules. To that end, it is handing over $20 million ...