Suboptimal biomarker testing rates persist in advanced cancers, with significant variation by cancer type, despite increasing trends over time. Comprehensive genomic profiling (CGP) enhances targeted ...
Somatic pathogenic genomic alterations in patients with SCBC, UC, and SCLC of any stage who underwent blood- or tissue-based genomic profiling through the Tempus assay were cataloged. Baseline ...
Early-stage lung adenocarcinoma with a micropapillary pattern showing a distinct immunogenic tumor microenvironment. Comparison and performance of three plasma next-generation sequencing assays versus ...
1 Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resources and Eco-Environment, College of Life Sciences, Sichuan University, Chengdu, China 2 Department of Gastrointestinal Surgery, ...
1 Department of Medical and Molecular Genetics, Indiana University School of Medicine, IU Health, Indianapolis, IN, USA 2 Department of Pediatrics, Indiana University School of Medicine, IU Health, ...
Gene duplications alter the genetic constitution of organisms and can be a driving force of molecular evolution in humans and the great apes. In this context, the study of genomic disorders has ...
Abstract: Genomic instability is one of fundamental factors in tumorigenesis and tumor progression. Many studies have demonstrated that copy-number abnormalities at the DNA level are important in the ...
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