Thomas Kleyman, MD, professor of medicine and chief of the renal-electrolyte division at the University of Pittsburgh Medical Center, is a senior author of the study. Sodium channels found outside the ...
Scientists have identified the first DNA sequence variant common in the population that is not only associated with an increased risk of heart failure, but appears to play a role in causing it. The ...
Rodent ClC-K1 and ClC-K2, and their respective human orthologs ClCKA and ClCKB, are chloride channels specific to the kidney (and inner ear); Barttin is their functionally important subunit. ClC-K1 is ...
We included crossover and parallel-arm randomized controlled trials examining the efficacy of L/N- and L/T-type CCBs as add-on treatment to an ACEI or ARB compared with the standard treatment group ...
Among older adults taking a calcium-channel blocker, simultaneous use of the antibiotic clarithromycin, compared with azithromycin, was associated with a small but statistically significant greater 30 ...
Nat Clin Pract Nephrol. 2008;4(1):38-46. Our knowledge of the localization, function, physiology and pathophysiology of the kidney-specific Cl-channels and Barttin has been greatly extended in the ...
Scientists have identified the first DNA sequence variant common in the population that is not only associated with an increased risk of heart failure, but appears to play a role in causing it. The ...
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