The inflammatory tumor microenvironment (TME) is a complex network of cancer, immune, and stromal cells interacting through cytokines and growth factors to drive tumor growth, angiogenesis, and immune ...

MILAN — Is chronic lymphocytic leukemia (CLL) progression primarily driven by genetic mutations or by external cues from the tumor microenvironment? Despite major strides in targeted therapies, CLL ...

Cutting both branches of the vagus nerve to the stomach or blocking its chemical signal with botulinum toxin (Botox) injections prevents the development and progression of gastric cancer in mouse ...

To effectively battle cancer, scientists must study the battlefield. Now, in a recent study published in Nature Communications, a multi-institutional research team including The University of Osaka ...

Combined epigenetic and immune checkpoint therapy altered the tumour microenvironment in platinum-resistant ovarian cancer.

Even before a tumor in the pancreas becomes discernible, an activated cancer gene actively remodels its future environment and creates an inflammatory and immune-defensive microenvironment in which ...

An interdisciplinary multi-center research team led by the LKS Faculty of Medicine (HKUMed) and Faculty of Dentistry at the University of Hong Kong has constructed the world's largest multi-omics ...

Researchers found that the Wnt5a protein, secreted by inflammatory fibroblasts within cancerous tumors, inhibits angiogenesis and consequently promotes hypoxia within tumors. Hypoxic conditions help ...

Bacteria-based cancer therapy harnesses bacteria to target cancer cells. Using bacteria to target tumors presents an exciting and innovative treatment option and could potentially be used when current ...

Cancer is often described as a genetic roll of the dice. A matter of bad luck. But new global estimates from the World Health ...