This systematic review and meta-analysis identified prognostic factors associated with early mortality in septic shock. The identification of these prognostic factors could aid in clinical risk ...

Early communication regarding prognosis and goals of care is crucial to ensuring a patient-centred approach to managing high-risk conditions such as septic shock. Identifying people at risk of poor ...

Background While female sex has historically been associated with worse outcomes following surgical aortic valve replacement, ...

Researchers conducted a systematic review of studies assessing the cost-effectiveness or cost-utility of adjuvant immunotherapy for treating various types of cancer.

Changes in the vaccine advisory process in the United States have disrupted immunization guidance, which reinforces the need for independent evidence review to inform decisions regarding immunization ...

Despite rapid advances in large language models, this study shows that human expertise remains critical for producing rigorous systematic reviews, with AI best suited as a supervised support tool ...

Objective This systematic review aims to evaluate the effectiveness of exercise interventions in alleviating depression and ...

Objective To examine the comprehensive health impacts of exercise on people with cancer by systematically summarising existing evidence and assessing the strength and reliability of the associations.

Objectives To examine the association between muscle strength and cardiorespiratory fitness (CRF) with all-cause and cancer-specific mortality in patients diagnosed with cancer, and whether these ...

Introduction High-risk pregnant women with physical or obstetric complications may develop depression and anxiety disorders that may worsen depending on the consequences of treatment and management ...