Nature

Gene transfer vector biodistribution: pivotal safety studies in clinical gene therapy development

In the field of gene transfer medicine, a range of vectors that have different properties might be used. On top of the intrinsic vector features, transgene and expression cassette characteristics as ...
VentureBeat

New DeepMind study reveals a hidden bottleneck in vector search that breaks advanced RAG systems

Vector embeddings are the backbone of modern enterprise AI, powering everything from retrieval-augmented generation (RAG) to semantic search. But a new study from Google DeepMind reveals a fundamental ...
GEN

High Dose AAV Vector Experiments Prove Extremely Toxic in Animal Studies

Gene Therapy Innovator Dr. James Wilson Raises Serious Concerns in New Report Gene therapy pioneer James M. Wilson, M.D., Ph.D., and colleagues have detailed in a new study, instances of severe, ...
Nature

INGN 007, an oncolytic adenovirus vector, replicates in Syrian hamsters but not mice: comparison of biodistribution studies

Preclinical biodistribution studies with INGN 007, an oncolytic adenovirus (Ad) vector, supporting an early stage clinical trial were conducted in Syrian hamsters, which are permissive for Ad ...