Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production ...

Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS).

New modeling shows how synonymous mutations -- those that change the DNA sequence of a gene but not the sequence of the encoded protein -- can still impact protein production and function. New ...

A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons. This is called the Wobble ...

Gene editing can repair mutations that prematurely halt protein synthesis, resulting in incomplete peptides that cause various diseases. However, other approaches achieve the same effect without ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...