PanMAN data structures compress pangenomes massively, encode evolutionary histories, and enable scalable analysis of millions of genomes.

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

Researchers at the University of California have created a novel data structure and compression method that allows ...

Engineers at the University of California have developed a new data structure and compression technique that enables the ...

Researchers have changed the way to look at DNA. They show that DNA is much more than a linear sequence of building blocks; it has a 3D structure that influences the variation of human genome-wide ...

Scientists have revealed parts of the genome that are especially vulnerable to mutations that occur very early on in development. These areas are in the initial portions of genes, where the cell tends ...

Announcing a new publication for Acta Materia Medica journal. Proteins are essential macromolecules that perform functions according to their conformational dynamics. Studying the conformational ...

High-accuracy single-molecule unique molecular identifier sequencing reveals non-random, biologically driven mutation heterogeneity within influenza quasi-species, enabling precise profiling of ...

A phylogenetic tree of SARS-CoV-2 sequences, built with Nextstrain, displays sequences colored by their clade and organized by collection date. Over time, sequences mutate and diverge, forming new ...

DURHAM, N.C. -- Researchers at Duke University's School of Medicine helped discover a new strain of coronavirus. Dr. David Montefiori, a professor of surgery who also serves as Director of the ...