Initial clinical experience with the first-in-class anti-metastasis therapeutic TTX-MC138. A phase 1 study of LB4330, a peptide fused to CLDN18.2 antibody targeting the tumor antigen associated (TAA) ...
Hangzhou Healthytide Biotechnology Co. Ltd. has synthesized peptoids acting as integrin α5β1 (ITGA5; VLA-5) antagonists reported to be useful for the treatment of cancer and macular degeneration.
-- Blocking of α5β1 integrin has been shown to improve motor function and increase survival in the SOD1G93A mouse model of ALS ---- Fully humanized anti-α5β1 monoclonal antibody is ready for ...
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