For decades, dopamine has been celebrated in neuroscience as the quintessential "reward molecule"—a chemical herald of ...

Researchers have found a small molecule enzyme inhibitor capable of manipulating an immune process that plays an important role in cancers and autoimmune diseases. Researchers at the University of ...

In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...

Antimicrobial design; targeted protein degradation; mTORC1 inhibition; enzyme structure-function studies. My laboratory uses approaches derived from both chemistry and biology. Projects include ...

Parkinson's is the most common, chronic neurodegenerative movement disorder affecting 1% of the global population over seventy years of age. Right now, there is no cure for this disease and the ...

An international study led by scientists at Flinders University and at South China University of Technology has uncovered a new vulnerability in prostate cancer cells that could help improve treatment ...

Georgetown University's Lombardi Comprehensive Cancer Center researchers have identified a new way to reprogram T cells, ...

Enzymes are the molecular machines that power life; they build and break down molecules, copy DNA, digest food, and drive ...

Iban Ubarretxena, an Ikerbasque Researcher and Director of the Biofisika Institute (CSIC-UPV/EHU), participates in a piece of research that has enabled new inhibitors to be identified and which could ...