Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

Findings suggest that new genes can form by repurposing fragments of ancestral genes while incorporating entirely new coding regions (the protein-coding parts of the DNA). This innovative concept ...

Researchers have created the most comprehensive map to date of DNA elements that regulate gene activity, nearly tripling the ...

In a recent study published in Nature, researchers in the United States aggregated and processed 76,156 human genomes to construct a genomic constraint map named "genomic non-coding constraint of ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species. Although mice share most ...

A new CRISPR breakthrough shows scientists can turn genes back on without cutting DNA, by removing chemical tags that act ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis ...

Researchers are investigating the role of non-coding DNA, or junk DNA, in regulating astrocytes, brain cells involved in ...

Humanized mouse models are vital for studying human gene function, but fully replacing mouse genes with complete human ...