A group of researchers at the University of Ottawa has been looking for ways to improve enzyme design methodologies and recently published their findings in Nature Communications. Enzymes are used in ...

Proteins are made of strings of amino acids that resemble the strand in the image above. Using machine learning models, researchers were able to design the identity of amino acids on a computer to ...

Directed evolution—a process in which a protein library is subjected to repeated rounds of mutation and selection to achieve desired properties—can improve the catalytic performance of computationally ...

Researchers have developed a new enzyme engineering platform to improve plastic degrading enzymes through directed evolution. Researchers from the Manchester Institute of Biotechnology (MIB) have ...

Researchers have shown how laboratory evolution can give rise to highly efficient enzymes for new-to-nature reactions, opening the door for novel and more environmentally friendly ways to make drugs ...

Enzymes catalyze chemical reactions in organisms—without which life would not be possible. Leveraging AlphaFold2 artificial intelligence, researchers at Charité—Universitätsmedizin Berlin have now ...

The combination of protein design and directed evolution is a powerful way to create enzymes with new functions. Now, Anthony P. Green and coworkers at the University of Manchester have thrown a ...

In nature, evolution takes years to sculpt new traits. In the lab, scientists hope to achieve this feat much faster: Being able to evolve proteins with enhanced or novel functions has important ...

Researchers at MIT have made a major breakthrough in optimizing rubisco, a key enzyme in photosynthesis. By modifying a bacterial version of this molecule, they achieved a 25% higher catalytic ...