Scientists developed a light-responsive artificial nucleic acid that enables reversible, controllable crosslinking within DNA, opening doors for nanomedicine, DNA nanotechnologies and drug delivery.

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

Epigenetic modifications such as DNA methylation play a key role in regulating gene expression. Emerging evidence suggests ...

Data from a new study in mice connects unrepaired DNA-protein crosslinks (DPCs), highly toxic tangles of protein and DNA, to inflammation-linked premature aging and embryonic lethality in mice. The ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal metabolic processes or external stressors such as radiation or chemical ...

DNA, the blueprint of life, is best known for its fundamental role as genetic material—storing and transmitting biological information through the precise sequence of its bases. For decades, this ...