Weighing the pros and cons of hot-melt extrusion and spray drying. The oral route remains the most preferred method for delivering drugs. It offers good patient compliance due to its acceptability, ...

Particle-engineering technologies, such as crystal design for crystallization and producting cocrystals, particle-size reduction, and amorphous solid dispersions, help to optimize delivery of a drug.

In industrial production, the surface of the compound may become amorphous due to a small amount of structural damage. It is difficult for conventional instruments to detect this small amount of ...